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AttributesValues
rdf:type
rdfs:label
  • Eltrombopag
rdfs:subClassOf
Has_Salt_Form
Has_Target
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Eltrombopag
UMLS_CUI
  • C1831905
CAS_Registry
  • 496775-61-2
FDA_UNII_Code
  • S56D65XJ9G
Contributing_Source
  • FDA
ALT_DEFINITION
  • The active ingredient in a drug used to treat chronic immune thrombocytopenic purpura (a condition in which platelets are destroyed by the immune system). It causes more platelets to be made in the bone marrow. It is also being studied in the treatment of low platelet counts caused by chemotherapy. It is a type of thrombopoietin receptor agonist.NCI-GLOSS
Chemical_Formula
  • C25H22N4O4
Legacy_Concept_Name
  • Eltrombopag_Base
FULL_SYN
  • EltrombopagPTNCI
  • eltrombopagPTNCI-GLOSSCDR0000628808
  • ELTROMBOPAGPTFDAS56D65XJ9G
DEFINITION
  • An orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity. Eltrombopag binds to and stimulates the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of megakaryocytes, thereby increasing the production of blood platelets.NCI
code
  • C71634
is Has_Free_Acid_Or_Base_Form of
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