About: Olivomycin

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Attributes	Values
rdf:type	Class
rdfs:label	Olivomycin
rdfs:subClassOf	DNA Minor Groove Binding Agent ANTINEOPLASTIC ANTIBIOTICS
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Antibiotic
Preferred_Name	Olivomycin
NSC_Code	76411
UMLS_CUI	C0028967
CAS_Registry	11006-70-5
FDA_UNII_Code	44003517D1
Contributing_Source	FDA
ALT_DEFINITION	A mixture of several closely related glycosidic antibiotics obtained from Actinomyces (or Streptomyces) olivoreticuli. They are used as fluorescent dyes that bind to DNA and prevent both RNA and protein synthesis and are also used as antineoplastic agents.MSH2002_06_01
Legacy_Concept_Name	Olivomycin_Antibiotic
CHEBI_ID	CHEBI:52515
FULL_SYN	Toyomycin RSYNCI OlivomycinsSYNCI Oligomycin A, mixt. with oligomycin BSYNCI OLIVOMYCINPTFDA44003517D1 OLIVOMYCINSYDTPNSC0076411 OlivomycinPTNCI
DEFINITION	A mixture of several closely related glycosidic antibiotics, obtained from Actinomyces (or Streptomyces) olivoreticuli with antifungal and antineoplastic activities. Olivomycin inhibits mitochondrial H+-ATP synthase. They are used as fluorescent dyes that bind to DNA and prevent both RNA and protein synthesis. In addition, olivomycin antibiotics are able to induce apoptosis in tumor cells through a mechanism that has not been fully elucidated.NCI
code	C715

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