About: HLA-DPA1 wt Allele     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • HLA-DPA1 wt Allele
rdfs:subClassOf
OMIM_Number
  • 142880
GenBank_Accession_Number
  • X00457
Semantic_Type
  • Gene or Genome
Preferred_Name
  • HLA-DPA1 wt Allele
UMLS_CUI
  • C2348921
EntrezGene_ID
  • 3113
Legacy_Concept_Name
  • HLA-DPA1_wt_Allele
HGNC_ID
  • HGNC:4938
FULL_SYN
  • DASS-32K24.2SYNCI
  • Major Histocompatibility Complex, Class II, DP Alpha 1 wt AlleleSYNCI
  • HLADPSYNCI
  • HLASBSYNCI
  • HLA-DPA1 wt AllelePTNCI
  • HLA DP1ASYNCI
DEFINITION
  • Human HLA-DPA1 wild-type allele is located in the vicinity of 6p21.3 and is approximately 16 kb in length. This allele, which encodes HLA class II histocompatibility antigen, DP alpha chain protein, is involved in the modulation of antigen presentation and T-cell mediated immunity. The gene is polymorphic and typing is often performed to determine histocompatibility for hematopoietic stem cell transplantation.NCI
DesignNote
  • The HLA-DPA1 gene is expressed as multiple isoforms that dimerize with HLA-DP beta chain proteins to form the HLA-DP complex.
code
  • C71268
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