About: Plant-Derived Hematopoiesis Enhancer PG2

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Attributes	Values
rdf:type	Class
rdfs:label	Plant-Derived Hematopoiesis Enhancer PG2
rdfs:subClassOf	Drug, Natural Product
Semantic_Type	Pharmacologic Substance
Preferred_Name	Plant-Derived Hematopoiesis Enhancer PG2
NCI_META_CUI	CL375858
PDQ_Open_Trial_Search_ID	570726
PDQ_Closed_Trial_Search_ID	570726
Legacy_Concept_Name	Plant-Derived_Hematopoiesis_Enhancer_PG2
FULL_SYN	PG2CNNCI Plant-Derived Hematopoiesis Enhancer PG2PTNCI
DEFINITION	A proprietary botanical formulation derived from a traditional Chinese medicinal (TCM) plant with hematopoietic activity. Although the mechanism of action has yet to be fully elucidated, plant-derived hematopoiesis enhancer PG2 appears to stimulate multi-lineage progenitor cells that may be closely related to the hematopoietic stem cell. In both chemotherapy- and radiation therapy-induced animal models of myelosuppression, this agent has been shown to restore granulocyte, erythrocyte, and platelet counts to normal levels. Plant-derived hematopoiesis enhancer PG2 stimulates the production of numerous cytokines such as granulocyte-colony stimulating factor (G-CSF) and may stimulate the production of neuroendocrine hormones.NCI
code	C70640

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