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AttributesValues
rdf:type
rdfs:label
  • Naproxen
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Naproxen
UMLS_CUI
  • C0700017
CAS_Registry
  • 22204-53-1
FDA_UNII_Code
  • 57Y76R9ATQ
Contributing_Source
  • FDA
ALT_DEFINITION
  • An anti-inflammatory agent with analgesic and antipyretic properties. Both the acid and its sodium salt are used in the treatment of rheumatoid arthritis and other rheumatic or musculoskeletal disorders, dysmenorrhea, and acute gout.MSH2002_06_01
  • A drug used to treat mild pain and the symptoms of arthritis and several other conditions. It is also being studied in the treatment of bone pain in patients with cancer. Naprosyn stops the body from making substances that cause pain and inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID) and a type of cyclooxygenase inhibitor.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 40222
PDQ_Closed_Trial_Search_ID
  • 40222
Chemical_Formula
  • C14H14O3
Legacy_Concept_Name
  • Naproxen
CHEBI_ID
  • CHEBI:7476
FULL_SYN
  • 6-Methoxy-alpha-methyl-2-naphthaleneacetic AcidSNNCI
  • NAPROXENPTFDA57Y76R9ATQ
  • RS-3540CNNCI
  • d-2-(6-Methoxy-2-naphthyl)propionic AcidSNNCI
  • NaprosynPTNCI-GLOSSCDR0000615395
  • naproxenPTNCI-GLOSSCDR0000615394
  • NaproxenPTNCI
  • NaprosynBRNCI
DEFINITION
  • A propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Naproxen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of naproxen. Naproxen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.NCI
code
  • C680
is Has_Free_Acid_Or_Base_Form of
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