About: Tocophersolan

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Tocophersolan
rdfs:subClassOf	Antioxidant
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance
Preferred_Name	Tocophersolan
UMLS_CUI	C0606070
CAS_Registry	9002-96-4
FDA_UNII_Code	O03S90U1F2
Contributing_Source	FDA
PDQ_Open_Trial_Search_ID	537550
PDQ_Closed_Trial_Search_ID	537550
Chemical_Formula	C33H54O5(C2H4O)n
Legacy_Concept_Name	Tocophersolan
FULL_SYN	d-Alpha Tocopheryl Polyethylene Glycol 1000 SuccinateSYNCI TOCOPHERSOLANPTFDAO03S90U1F2 TocophersolanPTNCI TPGSABNCI Vitamin E PEG-1000-SuccinateSYNCI
DEFINITION	A water-soluble amphipathic formulation of d-alpha-tocopherol succinate coupled, through a succinate linker, to polyethylene glycol (PEG) 1000. Due to its amphipathic property in which it forms its own micelles, tocophersolan is easily taken up into enterocytes, even in the absence of bile salts; fat soluble d-alpha-tocopherol is then released after hydrolysis. This formulation enhances the absorption of d-alpha-tocopherol compared to the administration of free d-alpha-tocopherol. In addition, tocophersolan may enhance the absorption of water-insoluble agents and other fat-soluble vitamins.NCI
code	C67044

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