About: Dyclonine Hydrochloride

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Attributes	Values
rdf:type	Class
rdfs:label	Dyclonine Hydrochloride
rdfs:subClassOf	ANESTHETICS
Has_Free_Acid_Or_Base_Form	DYCLONINE
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance
Preferred_Name	Dyclonine Hydrochloride
NSC_Code	23018
UMLS_CUI	C0304455
CAS_Registry	536-43-6
FDA_UNII_Code	ZEC193879Q
Contributing_Source	FDA
Chemical_Formula	C18H27NO2.HCl
Legacy_Concept_Name	Dyclonine_Hydrochloride
CHEBI_ID	CHEBI:4725
FULL_SYN	Dyclonine HydrochloridePTNCI 1-Propanone,1-(4-butoxyphenyl)-3-(1-piperidinyl)-,hydrochlorideSNNCI DYCLONINE HYDROCHLORIDEPTFDAZEC193879Q CepacolBRNCI DycloneBRNCI
DEFINITION	The hydrochloride salt of Dyclonine, an unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body.NCI
code	C66875
is Has_Salt_Form of	DYCLONINE

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