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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Pemirolast
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Pemirolast
UMLS_CUI
  • C0053881
CAS_Registry
  • 69372-19-6
FDA_UNII_Code
  • 2C09NV773M
Contributing_Source
  • FDA
Chemical_Formula
  • C10H8N6O
Legacy_Concept_Name
  • Pemirolast
FULL_SYN
  • 4H-Pyrido(1,2-a)Pyrimidin-4-One, 9-Methyl-3-(1H-Tetrazol-5-yl)-SNNCI
  • PEMIROLASTPTFDA2C09NV773M
  • PemirolastPTNCI
DEFINITION
  • A pyrimidinone derivative with anti-allergic activity. Pemirolast blocks the antigen-mediated calcium ion influx into mast cells. This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, such as histamine and leukotrienes, which are involved in the allergic process. Pemirolast also prevents inflammatory mediator release from eosinophils.NCI
code
  • C66334
is Has_Free_Acid_Or_Base_Form of
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