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AttributesValues
rdf:type
rdfs:label
  • Nebivolol
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Nebivolol
UMLS_CUI
  • C0068475
CAS_Registry
  • 118457-14-0
Accepted_Therapeutic_Use_For
  • Hypertension
FDA_UNII_Code
  • 030Y90569U
Contributing_Source
  • FDA
Chemical_Formula
  • C22H25F2NO4
Legacy_Concept_Name
  • Nebivolol
CHEBI_ID
  • CHEBI:64022
FULL_SYN
  • NEBIVOLOLPTFDA030Y90569U
  • BystolicBRNCI
  • NebivololPTNCI
DEFINITION
  • A beta-1 adrenergic receptor antagonist with antihypertensive and vasodilatory activity. Nebivolol binds to and blocks the beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, nebivolol potentiates nitric oxide (NO), thereby relaxing vascular smooth muscle and exerting a vasodilatory effect.NCI
code
  • C66221
is Has_Free_Acid_Or_Base_Form of
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