About: Micafungin Sodium     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Micafungin Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Micafungin Sodium
UMLS_CUI
  • C1576821
CAS_Registry
  • 208538-73-2
FDA_UNII_Code
  • IS1UP79R56
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 635524
PDQ_Closed_Trial_Search_ID
  • 635524
Chemical_Formula
  • C56H70N9O23S.Na
Legacy_Concept_Name
  • Micafungin_Sodium
FULL_SYN
  • Micafungin SodiumPTNCI
  • MICAFUNGIN SODIUMPTFDAIS1UP79R56
DEFINITION
  • The sodium salt form of micafungin, a semi-synthetic echinocandin derived from a natural product of the fungus Coleophoma empetri with antifungal activity. Micafungin, like other cyclic lipopeptides, noncompetitively inhibits the fungal specific enzyme 1,3-beta-D-glucan synthase, an enzyme essential for the synthesis of the important fungal cell wall component 1,3-beta-D-glucan. By preventing the synthesis of 1,3-beta-D-glucan, the cell wall is weakened which leads to osmotic lysis and eventually fungal cell death.NCI
code
  • C66145
is Has_Salt_Form of
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