About: Hyaluronidase, Ovine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Hyaluronidase, Ovine
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Hyaluronidase, Ovine
UMLS_CUI
  • C1577331
CAS_Registry
  • 488712-31-8
FDA_UNII_Code
  • 64R4OHP8T0
Contributing_Source
  • FDA
Legacy_Concept_Name
  • Hyaluronidase_Ovine
FULL_SYN
  • HYALURONIDASE, OVINEPTFDA64R4OHP8T0
  • VitraseBRNCI
  • Hyaluronidase, OvinePTNCI
DEFINITION
  • A highly purified preparation of ovine testicular hyaluronidase with potential chemoadjuvant activity. Upon subcutaneous administration, hyaluronidase modifies the permeability of connective tissue by hydrolyzing hyaluronic acid. This temporarily decreases interstitial viscosity and allows drugs that are co-injected to spread rapidly through the interstitial space, thereby facilitating absorption and/or distribution of co-injected agents.NCI
code
  • C65861
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