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AttributesValues
rdf:type
rdfs:label
  • Fenbenicillin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Fenbenicillin
UMLS_CUI
  • C1880750
CAS_Registry
  • 1926-48-3
FDA_UNII_Code
  • 641EDA6X6L
Contributing_Source
  • FDA
Chemical_Formula
  • C22H22N2O5S
Legacy_Concept_Name
  • Fenbenicillin
FULL_SYN
  • FENBENICILLINPTFDA641EDA6X6L
  • FenbenicillinPTNCI
DEFINITION
  • A semisynthetic phenoxy penicillin with antibacterial activity. Fenbenicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.NCI
code
  • C65639
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