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AttributesValues
rdf:type
rdfs:label
  • Mifepristone
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
  • Steroid
Preferred_Name
  • Mifepristone
NSC_Code
  • 652104
UMLS_CUI
  • C0026088
CAS_Registry
  • 84371-65-3
FDA_UNII_Code
  • 320T6RNW1F
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to end early pregnancies. It is also being studied in the treatment of some types of cancer and other conditions. Mifepristone blocks the action of progesterone, a hormone that helps some cancers grow. It is a type of antiprogesterone.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 40888
PDQ_Closed_Trial_Search_ID
  • 40888
Chemical_Formula
  • C29H35NO2
Legacy_Concept_Name
  • Mifepristone
CHEBI_ID
  • CHEBI:50692
FULL_SYN
  • MIFEPRISTONEPTFDA320T6RNW1F
  • MifepristoneSYDTPNSC0652104
  • MifepristonePTNCI
  • mifepristonePTNCI-GLOSSCDR0000045326
  • RU 486PTNCI-GLOSSCDR0000535560
  • 11 Beta-[4-(N,N-dimethylamino)phenyl]-17alpha-(propyl-1-ynyl)-delta-4,9-estradiene-17 beta-ol-3-oneSNNCI
  • RU 486CNNCI
  • RU-486CNNCI
  • KorlymBRNCI
  • RU-38486CNNCI
  • MifeprexPTNCI-GLOSSCDR0000535559
  • MifegyneFBNCI
  • 11-((4-dimethylamino) phenyl)-17-Hydroxy-17-(1-propynyl) Estra-4,9- dien-3-oneSNNCI
  • MifeprexBRNCI
  • (aa Beta, 17 beta)-11-[4-(dimethylamino)-phenyl]-17-hydroxy-17-(1-propynyl)estra-4,9-dien-3-oneSNNCI
DEFINITION
  • A derivative of the synthetic progestin norethindrone with antiprogesterone activity. Mifepristone competitively binds to the progesterone receptor, resulting in inhibition of the effects of endogenous or exogenous progesterone. This agent also exhibits antiglucocorticoid and weak antiandrogenic activities.NCI
code
  • C655
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