About: Cefonicid Sodium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cefonicid Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cefonicid Sodium
UMLS_CUI
  • C0886812
CAS_Registry
  • 61270-78-8
FDA_UNII_Code
  • F74MFL78A1
Contributing_Source
  • FDA
Chemical_Formula
  • C18H16N6O8S3.2Na
Legacy_Concept_Name
  • Cefonicid_Sodium
CHEBI_ID
  • CHEBI:3492
FULL_SYN
  • CEFONICID SODIUMPTFDAF74MFL78A1
  • Cefonicid SodiumPTNCI
DEFINITION
  • The sodium salt form of cefonicid, a semisynthetic second-generation cephalosporin with antibacterial activity. Cefonicid binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code
  • C65300
is Has_Salt_Form of
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