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AttributesValues
rdf:type
rdfs:label
  • Methoxsalen
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Methoxsalen
NSC_Code
  • 45923
UMLS_CUI
  • C0025684
CAS_Registry
  • 298-81-7
Accepted_Therapeutic_Use_For
  • Cutaneous T-cell lymphoma; psoriasis; vitiligo
In_Clinical_Trial_For
  • Chronic Graft vs Host disease; Hodgkins lymphoma; mycosis fungoides; myelodysplastic syndromes; Non-Hodgkins lymphoma
FDA_UNII_Code
  • U4VJ29L7BQ
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used together with UV light to treat psoriasis, vitiligo, and skin nodules of cutaneous T-cell lymphoma. It is also being studied in the treatment of graft-versus-host disease. It belongs to the family of drugs called psoralens and furocoumarins.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 39499
PDQ_Closed_Trial_Search_ID
  • 39499
Chemical_Formula
  • C12H8O4
Legacy_Concept_Name
  • Methoxsalen
CHEBI_ID
  • CHEBI:18358
FULL_SYN
  • MethoxsalenSYDTPNSC0045923
  • 9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-oneSNNCI
  • MethoxsalenPTNCI
  • PuvasoralenFBNCI
  • XanthotoxinBRNCI
  • 8-MOPSYDTPNSC0045923
  • DeltasoralenFBNCI
  • methoxsalenPTNCI-GLOSSCDR0000045224
  • MethoxsalenPTDCP00200
  • Oxsoralen-UltraBRNCI
  • MethoxypsoralenSYNCI
  • 8-MOPABNCI
  • AmmoidinSYDTPNSC0045923
  • 8-MethoxypsoralenSYNCI
  • DermoxFBNCI
  • UvadexBRNCI
  • GeralenFBNCI
  • OxsoralenSYDTPNSC0045923
  • AmmoidinBRNCI
  • UltramopFBNCI
  • 8-MethoxypsoralenSYDTPNSC0045923
  • MeladinineSYDTPNSC0045923
  • METHOXSALENPTFDAU4VJ29L7BQ
  • XANTHOTOXINSYDTPNSC0045923
  • GeroxalenFBNCI
  • OxsoralenBRNCI
  • MeladininaFBNCI
  • MeladinineFBNCI
  • MetoxalenoFBNCI
  • MopsoralenFBNCI
DEFINITION
  • A naturally occurring substance isolated from the seeds of the plant Ammi majus with photoactivating properties. As a member of the family of compounds known as psoralens or furocoumarins, methoxsalen's exact mechanism of action is unknown; upon photoactivation, methoxsalen has been observed to bind covalently to and crosslink DNA. (NCI04)NCI
code
  • C643
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