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AttributesValues
rdf:type
rdfs:label
  • Therapeutic Melatonin
rdfs:subClassOf
Concept_In_Subset
Is_Related_To_Endogenous_Product
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Therapeutic Melatonin
NSC_Code
  • 113928
  • 56423
UMLS_CUI
  • C1527137
CAS_Registry
  • 73-31-4
Accepted_Therapeutic_Use_For
  • Sleep disorders in blind people with no light perception
In_Clinical_Trial_For
  • Jet lag; seasonal affective disorder
FDA_UNII_Code
  • JL5DK93RCL
Contributing_Source
  • FDA
ALT_DEFINITION
  • A neurohormone synthesized by the pineal gland in mammals and by lower plants. Production peaks at night and secretion increases during exposure to light. In humans, it is implicated in the regulation of sleep, mood, puberty, and ovarian cycles. Evidence shows that melatonin is a highly effective free radical scavenger and antioxidant both in vivo and in vitro.MSH2002_06_01
PDQ_Open_Trial_Search_ID
  • 42346
PDQ_Closed_Trial_Search_ID
  • 42346
Chemical_Formula
  • C13H16N2O2
Legacy_Concept_Name
  • Therapeutic_Melatonin
CHEBI_ID
  • CHEBI:16796
FULL_SYN
  • MelatoninPTDCP00552
  • MELATONINPTFDAJL5DK93RCL
  • CircadinBRNCI
  • MelatoninSYNCI
  • Therapeutic MelatoninPTNCI
DEFINITION
  • A therapeutic chemically synthesized form of the pineal indole melatonin with antioxidant properties. The pineal synthesis and secretion of melatonin, a serotonin-derived neurohormone, is dependent on beta-adrenergic receptor function. Melatonin is involved in numerous biological functions including circadian rhythm, sleep, the stress response, aging, and immunity.NCI
code
  • C632
is someValuesFrom of
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