About: Beta-2-Microglobulin Protein

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Attributes	Values
rdf:type	Class
rdfs:label	Beta-2-Microglobulin Protein
rdfs:subClassOf	Immunoproteins nodeID://b650159 nodeID://b650160
OMIM_Number	109700
Semantic_Type	Amino Acid, Peptide, or Protein Biologically Active Substance
Preferred_Name	Beta-2-Microglobulin Protein
UMLS_CUI	C0005149
ALT_DEFINITION	A small protein normally found on the surface of many cells, including lymphocytes, and in small amounts in the blood and urine. An increased amount in the blood or urine may be a sign of certain diseases, including some types of cancer, such as multiple myeloma or lymphoma.NCI-GLOSS
Legacy_Concept_Name	Beta-2-Microglobulin_Protein
FULL_SYN	beta-2-microglobulinPTNCI-GLOSSCDR0000411372 Beta-2-Microglobulin ProteinPTNCI Beta-2-MicroglobinSYNCI
Swiss_Prot	Q540F8
DEFINITION	Beta-2-microglobulin protein (119 aa, ~14 kDa) is encoded by the human B2M gene. This protein plays a role in immune responses and is a key component of major histocompatibility complex class I molecules. The protein is localized to the surface of cells and is utilized as a prognostic marker in persons with cancers that involve white blood cells. The polypeptide is also used as a marker in kidney damage diagnosis and in the detection of viral infection.NCI
code	C62657

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