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AttributesValues
rdf:type
rdfs:label
  • Oxiglutatione
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Oxiglutatione
UMLS_CUI
  • C0061516
CAS_Registry
  • 27025-41-8
FDA_UNII_Code
  • ULW86O013H
Contributing_Source
  • FDA
Chemical_Formula
  • C20H32N6O12S2
Legacy_Concept_Name
  • Oxidized_Glutathione
CHEBI_ID
  • CHEBI:17858
FULL_SYN
  • L-Oxidized GlutathioneSYNCI
  • N-(N-gamma-glutamyl-cysteinyl)glycine-(2,2)-disulfideSNNCI
  • OXIGLUTATIONEPTFDAULW86O013H
  • OxigluthioneSYNCI
  • N,N'-(Dithiobis((R)-1-((carboxymethyl)carbamoyl)ethylene))di-L-glutamineSNNCI
  • OxiglutationePTNCI
  • GSSGABNCI
  • Bis(gamma-Glutamyl-L-cysteinylglycine) DisulfideSNNCI
  • Glutathione DisulfideSYNCI
DEFINITION
  • The oxidized disulfide form of glutathione (GSH) with potential protective activity. Glutathione disulfide (GSSG) is reduced by glutathione reductase to GSH. GSSG and GSH together play important roles in numerous redox reactions, such as those involved in the detoxification of harmful substances and free radicals, and in reactions preventing oxidative damage in erythrocytes. Upon ocular administration in irrigation solution, glutathione disulfide may exert a beneficial effect on the intracellular redox state of glutathione, thereby protecting the integrity and barrier function of the corneal endothelial cells.NCI
code
  • C62624
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