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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • 18F-FHBG
rdfs:subClassOf
Semantic_Type
  • Chemical
  • Indicator, Reagent, or Diagnostic Aid
Preferred_Name
  • 18F-FHBG
UMLS_CUI
  • C1453307
PDQ_Open_Trial_Search_ID
  • 488475
PDQ_Closed_Trial_Search_ID
  • 488475
Legacy_Concept_Name
  • _18F-FHBG
FULL_SYN
  • Reporter Probe 18F-FHBGSYNCI
  • 9-(4-18F-Fluoro-3-[hydroxymethyl]butyl)guanineSNNCI
  • 18F-FHBGPTNCI
DEFINITION
  • A fluorine-18-labeled acycloguanosine derivative substrate for herpes simplex virus type-1 thymidine kinase (HSV1-tk). 18F-FHBG is used as a reporter probe to image the expression of the herpes simplex virus type-1 thymidine kinase (HSV1-tk) gene in gene transfer therapy. HSV1-tk and HSV1-tk-metabolized 18F-FHBG co-localize, allowing positron emission tomography (PET) localization of HSV1-tk gene-transfected tissue and the assessment of gene transfer efficiency.NCI
code
  • C62533
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