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AttributesValues
rdf:type
rdfs:label
  • Trifluoperazine
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Trifluoperazine
UMLS_CUI
  • C0040979
CAS_Registry
  • 117-89-5
FDA_UNII_Code
  • 214IZI85K3
Contributing_Source
  • FDA
ALT_DEFINITION
  • A phenothiazine with actions similar to CHLORPROMAZINE. It is used as an antipsychotic and an antiemetic.MSH2002_06_01
Chemical_Formula
  • C21H24F3N3S
Legacy_Concept_Name
  • Trifluoperazine_Base
CHEBI_ID
  • CHEBI:45951
FULL_SYN
  • TFPABNCI
  • TRIFLUOPERAZINEPTFDA214IZI85K3
  • TrifluoperazinePTNCI
  • 10-(3-(4-Methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-10H-phenothiazineSNNCI
  • 10-[3-(4-Methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazinePTDCP05084
DEFINITION
  • A phenothiazine derivative and a dopamine antagonist with antipsychotic and antiemetic activities. Trifluoperazine exerts its antipsychotic effect by blocking central dopamine receptors, thereby preventing effects such as delusions and hallucinations caused by an excess of dopamine. This agent also functions as a calmodulin inhibitor, thereby leading to elevation of cytosolic calcium.NCI
code
  • C62084
is Has_Free_Acid_Or_Base_Form of
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