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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Quetiapine
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Quetiapine
UMLS_CUI
  • C0123091
CAS_Registry
  • 111974-69-7
FDA_UNII_Code
  • BGL0JSY5SI
Contributing_Source
  • FDA
Chemical_Formula
  • C21H25N3O2S
Legacy_Concept_Name
  • Quetiapine
CHEBI_ID
  • CHEBI:8707
FULL_SYN
  • QUETIAPINEPTFDABGL0JSY5SI
  • QuetiapinePTNCI
DEFINITION
  • A dibenzothiazepine derivative with antipsychotic property. Quetiapine fumarate antagonizes serotonin activity mediated by 5-HT 1A and 5-HT2 receptors. With a lower affinity, this agent also reversibly binds to dopamine D1 and D2 receptors in the mesolimbic and mesocortical areas of the brain leading to decreased psychotic effects, such as hallucinations and delusions. In addition, quetiapine also binds to other alpha-1, alpha-2 adrenergic and histamine H1 receptors.NCI
code
  • C61917
is Has_Free_Acid_Or_Base_Form of
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