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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Metoprolol
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Metoprolol
UMLS_CUI
  • C0025859
CAS_Registry
  • 51384-51-1
FDA_UNII_Code
  • GEB06NHM23
Contributing_Source
  • FDA
Chemical_Formula
  • C15H25NO3
Legacy_Concept_Name
  • Metoprolol
CHEBI_ID
  • CHEBI:6904
FULL_SYN
  • MetoprololPTDCP30286
  • METOPROLOLPTFDAGEB06NHM23
  • MetoprololPTNCI
DEFINITION
  • A cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction leading to a reduction in cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thereby preventing vasoconstriction and aldosterone secretion.NCI
code
  • C61845
is Has_Free_Acid_Or_Base_Form of
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