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AttributesValues
rdf:type
rdfs:label
  • Ipratropium
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ipratropium
UMLS_CUI
  • C0027235
CAS_Registry
  • 60205-81-4
FDA_UNII_Code
  • GR88G0I6UL
Contributing_Source
  • FDA
Chemical_Formula
  • C20H30NO3
Legacy_Concept_Name
  • Ipratropium_Cation
CHEBI_ID
  • CHEBI:5956
FULL_SYN
  • IpratropiumPTNCI
  • (3-endo,8-syn)-3-(3-Hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo(3.2.1)octaneSNNCI
  • IPRATROPIUMPTFDAGR88G0I6UL
DEFINITION
  • A synthetic derivative of the alkaloid atropine with anticholinergic properties. Ipratropium antagonizes the actions of acetylcholine at parasympathetic postganglionic effector cell junctions. When inhaled, ipratropium binds competitively to cholinergic receptors in the bronchial smooth muscle thereby blocking the bronchoconstrictor actions of the acetylcholine (Ach) mediated vagal impulses. Inhibition of the vagal tone leads to dilation of the large central airways resulting in bronchodilation.NCI
code
  • C61794
is Has_Free_Acid_Or_Base_Form of
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