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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Epoprostenol
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Epoprostenol
UMLS_CUI
  • C0033567
CAS_Registry
  • 35121-78-9
FDA_UNII_Code
  • DCR9Z582X0
Contributing_Source
  • FDA
Chemical_Formula
  • C20H32O5
Legacy_Concept_Name
  • Epoprostenol
CHEBI_ID
  • CHEBI:15552
FULL_SYN
  • EPOPROSTENOLPTFDADCR9Z582X0
  • EpoprostenolPTNCI
DEFINITION
  • An oral prostacyclin and a metabolite of arachidonic acid with antihypertensive and platelet inhibitory properties. Epoprostenol binds to prostacyclin receptors on platelet surfaces, subsequently activating platelet membrane adenyl cyclase and resulting in increased cAMP levels. The elevated cAMP triggers signal transduction that leads to vasodilations. In addition, this agent also functions as an antagonist of thromboxane A2, thereby resulting in direct vasodilation of pulmonary and systemic arterial vascular beds, and inhibition of platelet aggregation.NCI
code
  • C61748
is Has_Free_Acid_Or_Base_Form of
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