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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Digitalin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Digitalin
UMLS_CUI
  • C0058012
CAS_Registry
  • 752-61-4
FDA_UNII_Code
  • Q15ECE254B
Contributing_Source
  • FDA
Chemical_Formula
  • C36H56O14
Legacy_Concept_Name
  • Digitalin
CHEBI_ID
  • CHEBI:28143
FULL_SYN
  • DIGITALINPTFDAQ15ECE254B
  • DigitalinPTNCI
DEFINITION
  • A glycoside compound, extracted from the leaves and seeds of the common foxglove, with anti-arrhythmic property. Digitalin inhibits the enzymatic activity of the sodium-potassium ATPase pump in cardiac tissue, thereby increasing intracellular sodium and calcium levels and providing a positive inotropic effect. This results in increased force of myocardial muscle contraction. This agent also has a vagal effect on the parasympathetic nervous system, and as such slows the ventricular heart rate as well as helps eliminate fluid from body tissues.NCI
code
  • C61723
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