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AttributesValues
rdf:type
rdfs:label
  • Cloxacillin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cloxacillin
UMLS_CUI
  • C0009077
CAS_Registry
  • 61-72-3
FDA_UNII_Code
  • O6X5QGC2VB
Contributing_Source
  • FDA
Chemical_Formula
  • C19H18ClN3O5S
Legacy_Concept_Name
  • Cloxacillin
CHEBI_ID
  • CHEBI:49566
FULL_SYN
  • CloxacillinPTNCI
  • CLOXACILLINPTFDAO6X5QGC2VB
DEFINITION
  • A semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity. Cloxacillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial cell lysis.NCI
code
  • C61688
is Has_Free_Acid_Or_Base_Form of
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