About: Cefoperazone     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Cefoperazone
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cefoperazone
UMLS_CUI
  • C0007552
CAS_Registry
  • 62893-19-0
FDA_UNII_Code
  • 7U75I1278D
Contributing_Source
  • FDA
Chemical_Formula
  • C25H27N9O8S2
Legacy_Concept_Name
  • Cefoperazone
CHEBI_ID
  • CHEBI:3493
FULL_SYN
  • CEFOPERAZONEPTFDA7U75I1278D
  • CefoperazonePTNCI
DEFINITION
  • A semisynthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity. Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code
  • C61663
is Has_Free_Acid_Or_Base_Form of
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