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AttributesValues
rdf:type
rdfs:label
  • Carboprost
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Carboprost
UMLS_CUI
  • C0007047
CAS_Registry
  • 35700-23-3
FDA_UNII_Code
  • 7B5032XT6O
Contributing_Source
  • FDA
Chemical_Formula
  • C21H36O5
Legacy_Concept_Name
  • Carboprost
CHEBI_ID
  • CHEBI:3403
FULL_SYN
  • Prostin 15MSYNCI
  • (15S)-15-Methyl-PGF2alphaSNNCI
  • Methyl-PGF2-alphaSYNCI
  • U 32921CNNCI
  • CARBOPROSTPTFDA7B5032XT6O
  • CarboprostPTNCI
DEFINITION
  • The (15S)-15 methyl analogue of naturally occurring prostaglandin F2 alpha (PGF2 alpha) with oxytocic activity. Mimicking endogenous PGF2 alpha, carboprost activates prostaglandin F receptor, a G-protein coupled receptor, on smooth muscle cells, thereby resulting in smooth muscle contractions. When administered intramuscularly on gravid subjects, this agent induces myometrium contractions, thereby initiating luteolysis and consequently parturition. Furthermore, carboprost's action on vascular smooth muscle and gastrointestinal tract sphincters leads to raised blood pressure and induces vomiting or diarrhea, respectively.NCI
code
  • C61662
is Has_Free_Acid_Or_Base_Form of
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