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AttributesValues
rdf:type
rdfs:label
  • Betaxolol
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Betaxolol
UMLS_CUI
  • C0005320
CAS_Registry
  • 63659-18-7
FDA_UNII_Code
  • O0ZR1R6RZ2
Contributing_Source
  • FDA
Chemical_Formula
  • C18H29NO3
Legacy_Concept_Name
  • Betaxolol
CHEBI_ID
  • CHEBI:3082
FULL_SYN
  • BETAXOLOLPTFDAO0ZR1R6RZ2
  • 1-(4-(2-Cyclopropylmethoxy)ethyl)phenoxy)-3-))1-methylethyl)amino)-2-propanolSNNCI
  • BetaxololPTNCI
DEFINITION
  • A racemic mixture and selective beta-1 adrenergic receptor antagonist with antihypertensive and anti-glaucoma activities and devoid of intrinsic sympathomimetic activity. Betaxolol selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. When applied topically in the eye, this agent reduces aqueous humor secretion and lowers the intraocular pressure (IOP). In addition, betaxolol prevents the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels.NCI
code
  • C61652
is Has_Free_Acid_Or_Base_Form of
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