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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • SU014813
rdfs:subClassOf
Has_Target
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • SU014813
UMLS_CUI
  • C1831849
PDQ_Open_Trial_Search_ID
  • 486831
PDQ_Closed_Trial_Search_ID
  • 486831
Legacy_Concept_Name
  • SU014813
FULL_SYN
  • SU014813PTNCI
DEFINITION
  • An orally-active, tyrosine kinase receptor inhibitor with potential antitumor activity. SU014813 binds to and inhibits the phosphorylation of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor (PDGFR) alpha and beta, c-Kit and Fms-related tyrosine kinase 3 (Flt-3). This leads to an inhibition of cellular proliferation and angiogenesis and an induction of apoptosis.NCI
code
  • C61507
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