About: Xaliproden Hydrochloride

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Attributes	Values
rdf:type	Class
rdfs:label	Xaliproden Hydrochloride
rdfs:subClassOf	Immunomodulating Agent
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance
Preferred_Name	Xaliproden Hydrochloride
UMLS_CUI	C0247952
CAS_Registry	90494-79-4
FDA_UNII_Code	44D5EE8E26
Contributing_Source	FDA
PDQ_Open_Trial_Search_ID	480399
PDQ_Closed_Trial_Search_ID	480399
Chemical_Formula	C24H22F3N.ClH
Legacy_Concept_Name	Xaliproden_Hydrochloride
FULL_SYN	Xaliproden HydrochloridePTNCI 1,2,3,6-tetrahydro-1-[2-(2-naphthalenyl)ethyl]-4-(3-(trifluoromethyl)phenyl)pyridine HydrochlorideSNNCI XALIPRODEN HYDROCHLORIDEPTFDA44D5EE8E26 SR-57746ACNNCI
DEFINITION	The hydrochloride salt of xaliproden, an orally-active, synthetic, non-peptidic 5-hydroxytryptamine (5-HT) 1A receptor agonist with neurotrophic and neuroprotective activities. Although its mechanism of action is not fully understood, xaliproden appears to either mimic the effects of neurotrophins or stimulate their synthesis, thereby stimulating neuronal cell differentiation and proliferation and inhibiting neuronal cell death. The neuroprotective effect of this agent involves the activation of MAP kinase pathways via stimulation of the 5-HT1A receptor.NCI
code	C61328

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