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AttributesValues
rdf:type
rdfs:label
  • Recombinant Interleukin
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Recombinant Interleukin
UMLS_CUI
  • C1527200
Legacy_Concept_Name
  • Therapeutic_Interleukin
FULL_SYN
  • InterleukinsSYNCI
  • Recombinant InterleukinPTNCI
DEFINITION
  • Formulated therapeutic analogs of one of a number of endogenous cytokine interleukins. Produced by T cells, macrophages, and other cells, interleukins bind to a specific surface receptor on immunohematopoietic cells, thereby inducing a multitude of biologic effects including stimulation of growth, differentiation, and proliferation of lymphocytes and eosinophils; activation of lymphocytes and macrophages; enhancement of mast cell activity; activation of the acute phase response; and stimulation of hematopoiesis. Some interleukins may enhance the host's immune response to malignant cells by stimulating lymphokine-activated killer (LAK) cells and tumor-infiltrating lymphocytes (TIL), which are capable of lysing some tumor cells. (NCI04)NCI
code
  • C593
is rdf:first of
is rdfs:subClassOf of
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