About: Recombinant Interleukin-3

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Attributes	Values
rdf:type	Class
rdfs:label	Recombinant Interleukin-3
equivalentClass	nodeID://b640575
Semantic_Type	Amino Acid, Peptide, or Protein Pharmacologic Substance
Preferred_Name	Recombinant Interleukin-3
NSC_Code	641115
UMLS_CUI	C1527130
PDQ_Open_Trial_Search_ID	38970
PDQ_Closed_Trial_Search_ID	38970
Legacy_Concept_Name	Therapeutic_Interleukin-3
FULL_SYN	Colony-Stimulating Factor 2 AlphaSYNCI Eosinophil-Mast Cell Growth-FactorSYNCI Erythrocyte Burst-Promoting FactorSYNCI Mast-Cell Colony-Stimulating FactorSYNCI MCGFABNCI Multipotential Colony-Stimulating FactorSYNCI Interleukin-3SYNCI Recombinant Interleukin-3PTNCI IL-3ABNCI ILE-964CNNCI
DEFINITION	A recombinant form of interleukin-3, a cytokine produced by activated T-cells and mast cells involved in intercellular communication, hematopoiesis, and inflammation. IL-3 binds and activates specific receptors on hematopoietic cells and in the nervous system, triggering expression of specific genes via the Ras signaling pathway and through Jak2 activation. This agent stimulates the proliferation of pluripotent hematopoietic progenitor cells.NCI
code	C588
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