About: Recombinant Interleukin-2     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Recombinant Interleukin-2
equivalentClass
Has_Target
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Recombinant Interleukin-2
NSC_Code
  • 373364
UMLS_CUI
  • C0919268
Accepted_Therapeutic_Use_For
  • Colorectal cancer; metastatic melanoma; metastatic renal cell carcinoma; Non-Hodgkins lymphoma
In_Clinical_Trial_For
  • Breast cancer; cancer of mouth or oropharynx; colorectal cancer; HIV infections; leukemia; lymphoma; melanoma; mycosis fungoides; myelodysplastic syndromes; neuroblastoma
  • Ovarian neoplasm; prostate cancer; renal cell carcinoma; unspecified solid tumors; Wegners granulomatosis
ALT_DEFINITION
  • One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-2 is made by a type of T lymphocyte. It increases the growth and activity of other T lymphocytes and B lymphocytes, and affects the development of the immune system. Aldesleukin (interleukin-2 made in the laboratory) is being used as a biological response modifier to boost the immune system in cancer therapy. Interleukin-2 is a type of cytokine.NCI-GLOSS
Legacy_Concept_Name
  • Therapeutic_Interleukin-2
FULL_SYN
  • Interleukin IISYNCI
  • TSFABNCI
  • TCGFABNCI
  • Mitogenic FactorSYNCI
  • Lymphocyte Mitogenic FactorSYNCI
  • Thymocyte Stimulating FactorSYNCI
  • T-Cell Growth FactorSYNCI
  • IL-2PTNCI-GLOSSCDR0000044367
  • Interleukin-2SYNCI
  • Recombinant Interleukin-2PTNCI
  • IL-2ABNCI
  • interleukin-2SYNCI-GLOSSCDR0000045256
  • Ro-236019CNNCI
  • Recombinant interleukin-2SYDTPNSC0373364
DEFINITION
  • Any recombinant analog of endogenous interleukin-2 (IL-2), a cytokine involved in intercellular communication related to cell differentiation, proliferation, inflammation, hematopoiesis, neuronal functions, and release of hormones. IL-2 binds to and activates specific receptors, triggering expression of specific genes, and may induce T cell-mediated tumor regression in some tumor types.NCI
code
  • C587
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is rdfs:subClassOf of
is someValuesFrom of
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