About: Immunotoxin

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Attributes	Values
rdf:type	Class
rdfs:label	Immunotoxin
rdfs:subClassOf	Immunoconjugates Biological Products
Semantic_Type	Chemical Viewed Functionally
Preferred_Name	Immunotoxin
UMLS_CUI	C0021084
ALT_DEFINITION	An antibody linked to a toxic substance. Some immunotoxins can bind to cancer cells and kill them.NCI-GLOSS
Legacy_Concept_Name	Immunotoxin
FULL_SYN	ImmunotoxinPTNCI immunotoxinPTNCI-GLOSSCDR0000045730
DEFINITION	Agents comprised of various toxic molecules (Radioactive Isotopes and Bacterial or Plant Toxins) conjugated with specific immune substances (Immunoglobulins, Monoclonal Antibodies, and Antigens) that targets affected cells allowing incorporation of the toxin into the cells.NCI
code	C575
is rdfs:subClassOf of	TP3 Immunotoxin Transferrin-CRM107 Anti-Myeloma Monoclonal Antibody-DM4 Immunoconjugate BT-062 Denileukin Diftitox CD30 Immunotoxin CD22 Immunotoxin Anti-CD19 Immunotoxins Anti-CD33 Immunotoxin Ricin Immunoconjugate Anti-CD7 Immunotoxin DTGM Fusion Protein Anti-Dopamine-b-Hydroxylase Monoclonal Antibody-Saporin Lorvotuzumab Mertansine Anti-EpCAM Antibody Fragment-Pseudomonas-exotoxin Fusion Protein Cantuzumab Ravtansine Immunotoxin CMD-193 DT(388)IL3 Fusion Protein Inotuzumab Ozogamicin Citatuzumab Bogatox Anti-CD3 Immunotoxin A-dmDT390-bisFv(UCHT1) DM4-Conjugated Anti-Cripto Monoclonal Antibody BIIB015 Glembatumumab Vedotin Pseudomonas Exotoxin Immunoconjugate Anti-Integrin Monoclonal Antibody-DM4 Immunoconjugate IMGN388 Anti-EphA2 Monoclonal Antibody-MMAF Immunoconjugate MEDI-547 Anti-CD19/Anti-CD22 Bispecific Immunotoxin DT2219ARL Anti-EGFRvIII Immunotoxin MR1-1 Anti-EGP-2 Immunotoxin MOC31-PE Anti-CA6-DM4 Immunoconjugate SAR566658 Anti-EGFRvIII Antibody Drug Conjugate AMG 595

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