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AttributesValues
rdf:type
rdfs:label
  • Integrin Beta-5
rdfs:subClassOf
OMIM_Number
  • 147561
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Integrin Beta-5
UMLS_CUI
  • C0249042
Legacy_Concept_Name
  • ITGB5_Protein
FULL_SYN
  • ITGB5 ProteinSYNCI
  • Integrin Beta-5PTNCI
  • Integrin, Beta 5SYNCI
Swiss_Prot
  • P18084
DEFINITION
  • Integrin beta-5 (799 aa, ~88 kDa) is encoded by the human ITGB5 gene. This type I membrane protein forms a heterodimer with integrin alpha-V protein. The resulting complex binds to the tripeptide R-G-D, an amino acid sequence present in a number of ligands including vitronectin, fibronectin, fibrinogen, and laminin. Ligand binding regulates cell adhesion, growth and migration.NCI
code
  • C53962
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