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AttributesValues
rdf:type
rdfs:label
  • Citrulline
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Citrulline
NSC_Code
  • 27425
UMLS_CUI
  • C0008864
CAS_Registry
  • 372-75-8
FDA_UNII_Code
  • 29VT07BGDA
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 464795
PDQ_Closed_Trial_Search_ID
  • 464795
Chemical_Formula
  • C6H13N3O3
Legacy_Concept_Name
  • Citrulline
CHEBI_ID
  • CHEBI:16349
FULL_SYN
  • L-CitrullineSYNCI
  • 2-Amino-5-(carbamoylamino)pentanoic AcidSNNCI
  • CITRULLINEPTFDA29VT07BGDA
  • N5-(Aminocarbonyl)-L-ornithineSNNCI
  • CitrullinePTNCI
DEFINITION
  • A non-essential amino acid. In hepatocytes, L-citrulline is synthesized in the urea cycle by the addition of carbon dioxide and ammonia to ornithine. L-citrulline is converted into L-arginine by the enzymes argininosuccinate synthetase and argininosuccinate lyase in the presence of L-aspartate and ATP. Subsequently, L-arginine is converted to nitric oxide by nitric oxide synthase and L-citrulline is regenerated as a by-product.NCI
code
  • C53406
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