About: FOXO3 wt Allele     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • FOXO3 wt Allele
equivalentClass
OMIM_Number
  • 602681
GenBank_Accession_Number
  • NM_001455
Semantic_Type
  • Gene or Genome
Preferred_Name
  • FOXO3 wt Allele
UMLS_CUI
  • C2348503
GO_Annotation
  • induction of apoptosisGO:0006917TAS29-SEP-2003CGAP
  • nucleusGO:0005634TAS29-SEP-2003CGAP
  • transcription from Pol II promoterGO:0006366TAS29-SEP-2003CGAP
  • cytoplasmGO:0005737TAS29-SEP-2003CGAP
EntrezGene_ID
  • 2309
Legacy_Concept_Name
  • FOXO3A_wt_Allele
HGNC_ID
  • HGNC:3821
FULL_SYN
  • FOXO3A GeneSYNCI
  • Forkhead Box O3 wt AlleleSYNCI
  • FOXO3 wt AllelePTNCI
  • FOXO2SYNCI
  • FOXO3SYNCI
  • AF6q21SYNCI
  • FKHRL1SYNCI
  • Forkhead Box O3A GeneSYNCI
Gene_Encodes_Product
  • Forkhead Box O3A
DEFINITION
  • Human FOXO3 wild-type allele is located in the vicinity of 6q21 and is approximately 121 kb in length. This allele, which encodes forkhead box protein O3A, plays a role in the activation of both transcription by RNA polymerase II and apoptosis that is induced by oxidative stress.NCI
DesignNote
  • The FOXO3A gene product recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3' (GeneCards).
code
  • C52907
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