About: FGF8 wt Allele     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • FGF8 wt Allele
equivalentClass
OMIM_Number
  • 600483
GenBank_Accession_Number
  • NM_006119
Semantic_Type
  • Gene or Genome
Preferred_Name
  • FGF8 wt Allele
UMLS_CUI
  • C1706606
GO_Annotation
  • growth factor activityGO:0008083NR29-SEP-2003CGAP
  • embryogenesis and morphogenesisGO:0007345TAS29-SEP-2003CGAP
  • developmentGO:0007275TAS29-SEP-2003CGAP
  • cellular_component unknownGO:0008372NAS29-SEP-2003CGAP
  • growth factor activityGO:0008083NAS29-SEP-2003CGAP
  • gastrulationGO:0007369TAS29-SEP-2003CGAP
  • cell-cell signalingGO:0007267NR29-SEP-2003CGAP
  • cell proliferationGO:0008283NAS29-SEP-2003CGAP
  • extracellular spaceGO:0005615NR29-SEP-2003CGAP
  • signal transductionGO:0007165NR29-SEP-2003CGAP
EntrezGene_ID
  • 2253
Legacy_Concept_Name
  • FGF8_wt_Allele
HGNC_ID
  • HGNC:3686
FULL_SYN
  • FGF8 wt AllelePTNCI
  • Fibroblast Growth Factor 8 (Androgen-Induced) wt AlleleSYNCI
  • AIGFSYNCI
  • HBGF-8SYNCI
Gene_Encodes_Product
  • Fibroblast Growth Factor 8
DEFINITION
  • Human FGF8 wild-type allele is located within 10q24 and is approximately 6 kb in length. This allele, which encodes fibroblast growth factor 8 protein, plays a role in embryonic epithelial regulation and angiogenesis.NCI
DesignNote
  • Human FG8F Gene (FGF Family) at 10q24 encodes alternative isoforms FGF-8A, FGF-8B, FGF-8E, and FGF-8F of secreted autocrine androgen-induced Fibroblast Growth Factor 8, which may be involved in angiogenesis and/or act as an embryonic epithelial factor in midbrain and limb development, in organogenesis, in gastrulation, and in left-right axis determination. Additional isoforms may exist.
code
  • C51503
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