About: SERPINI2 wt Allele     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • SERPINI2 wt Allele
equivalentClass
OMIM_Number
  • 605587
GenBank_Accession_Number
  • NM_006217
Semantic_Type
  • Gene or Genome
Preferred_Name
  • SERPINI2 wt Allele
UMLS_CUI
  • C1705805
GO_Annotation
  • cell motilityGO:0006928TAS29-SEP-2003CGAP
  • serpinGO:0004868TAS29-SEP-2003CGAP
EntrezGene_ID
  • 5276
Legacy_Concept_Name
  • SERPINI2_wt_Allele
HGNC_ID
  • HGNC:8945
FULL_SYN
  • Serine (or Cysteine) Proteinase Inhibitor, Clade I (Pancpin), Member 2 wt AlleleSYNCI
  • PI14SYNCI
  • MEPISYNCI
  • SERPINI2 wt AllelePTNCI
  • TSA2004SYNCI
  • PANCPINSYNCI
  • SERPIN12SYNCI
Gene_Encodes_Product
  • Protease Inhibitor 14
DEFINITION
  • Human SERPINI2 wild-type allele is located within 3q26.1-q26.2 and is approximately 32 kb in length. This allele, which encodes serpin I2 protein, is involved in the inhibition of serine protease enzymes.NCI
DesignNote
  • The SERPINI2 gene has been shown to be down-regulated in pancreatic cancer cell lines compared to normal pancreatic tissues. Expression of this gene has been shown to be abolished in breast carcinomas. The SERPINI2 gene is suggested to be a candidate tumor suppressor gene which prevents the development or progression of cancer.
code
  • C51410
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