About: SERPINB2 wt Allele     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • SERPINB2 wt Allele
equivalentClass
OMIM_Number
  • 173390
GenBank_Accession_Number
  • NM_002575
Semantic_Type
  • Gene or Genome
Preferred_Name
  • SERPINB2 wt Allele
UMLS_CUI
  • C1705218
EntrezGene_ID
  • 5055
Legacy_Concept_Name
  • SERPINB2_wt_Allele
HGNC_ID
  • HGNC:8584
FULL_SYN
  • Serine (or Cysteine) Proteinase Inhibitor, Clade B (Ovalbumin), Member 2 wt AlleleSYNCI
  • PAI2SYNCI
  • PLANH2SYNCI
  • SERPINB2 wt AllelePTNCI
Gene_Encodes_Product
  • Plasminogen Activator Inhibitor-2
DEFINITION
  • Human SERPINB2 wild-type allele is located in the vicinity of 18q21.3 and is approximately 16 kb in length. This allele, which encodes plasminogen activator inhibitor 2 protein, is involved in the inhibition of urokinase-type plasminogen activator.NCI
DesignNote
  • Up-regulation of SERPINB2 gene expression is associated with inhibition of metastasis and a better prognosis for cancer patients. This gene is expressed in keratinocytes, macrophages, monocytes, placenta, and the trophoblast.
code
  • C51406
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