About: PIK3CB wt Allele     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • PIK3CB wt Allele
equivalentClass
OMIM_Number
  • 602925
GenBank_Accession_Number
  • NM_006219
Semantic_Type
  • Gene or Genome
Preferred_Name
  • PIK3CB wt Allele
UMLS_CUI
  • C1705590
GO_Annotation
  • activation of MAPKGO:0000187TAS29-SEP-2003CGAP
  • signal transductionGO:0007165NR29-SEP-2003CGAP
  • G-protein coupled receptor protein signaling pathwayGO:0007186TAS29-SEP-2003CGAP
  • regulation of cell cycleGO:0000074TAS29-SEP-2003CGAP
  • chemotaxisGO:0006935TAS29-SEP-2003CGAP
  • phosphatidylinositol 3-kinase activityGO:0016303TAS29-SEP-2003CGAP
EntrezGene_ID
  • 5291
Legacy_Concept_Name
  • PIK3CB_wt_Allele
HGNC_ID
  • HGNC:8976
FULL_SYN
  • Phosphoinositide-3-Kinase, Catalytic, Beta Polypeptide wt AlleleSYNCI
  • PIK3CB wt AllelePTNCI
  • PIK3C1SYNCI
  • p110-BetaSYNCI
Gene_Encodes_Product
  • Phosphoinositide-3-Kinase Catalytic Beta Polypeptide
DEFINITION
  • Human PIK3CB wild-type allele is located in the vicinity of 3q22.3 and is approximately 105 kb in length. This allele, which encodes phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform protein, plays a role in signaling pathways underlying the regulation of apoptosis, cell growth, and angiogenesis.NCI
code
  • C51161
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