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AttributesValues
rdf:type
rdfs:label
  • Endotoxin
rdfs:subClassOf
Semantic_Type
  • Organic Chemical
Preferred_Name
  • Endotoxin
UMLS_CUI
  • C0014264
Legacy_Concept_Name
  • Endotoxin
FULL_SYN
  • Bacterial PyrogenSYNCI
  • EndotoxinPTNCI
  • EndotoxinsSYNCI
DEFINITION
  • The lipopolysaccharide complexes that are part of the outer membrane of the cell wall of Gram-negative bacteria such as E. coli, Salmonella, Shigella, Pseudomonas, Neisseria, Haemophilus, and other leading pathogens. Upon bacterial infections, the lipid component (Lipid A) of endotoxin contributes to its toxicity, while the polysaccharide components contribute to immunogenicity.NCI
code
  • C50918
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