About: Flecainide Acetate

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Flecainide Acetate
rdfs:subClassOf	ANTIARRHYTHMICS Cation Channel Blocker nodeID://b673678
Has_Free_Acid_Or_Base_Form	FLECAINIDE
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Organic Chemical Pharmacologic Substance
Preferred_Name	Flecainide Acetate
NSC_Code	719273
UMLS_CUI	C0086303
CAS_Registry	54143-56-5
FDA_UNII_Code	M8U465Q1WQ
Contributing_Source	FDA
PDQ_Open_Trial_Search_ID	41626
PDQ_Closed_Trial_Search_ID	41626
Chemical_Formula	C17H20F6N2O3.C2H4O2
Legacy_Concept_Name	Flecainide
FULL_SYN	Flecainide AcetatePTNCI FLECAINIDE ACETATEPTFDAM8U465Q1WQ
DEFINITION	The acetate salt form of flecainide, a synthetic agent derived from trifluoroethoxy-benzamide exhibiting antiarrhythmic and local anesthetic activity. As a class Ic antiarrhythmic that blocks sodium channels, flecainide depresses polarization phase 0 and decreases the induction velocity of the His-Purkinje system. It also decreases phase 4 slope and increases the depolarization threshold.NCI
DesignNote	Flecainide is used to prevent paroxysmal supraventricular tachycardias, atrial fibrillations and flutter, and other arrhythmias. It also relieves neuropathic pain from damage to nerves caused by some cancers.
code	C499
is Has_Salt_Form of	FLECAINIDE

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