About: CCL18 wt Allele     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • CCL18 wt Allele
equivalentClass
OMIM_Number
  • 603757
GenBank_Accession_Number
  • NM_002988
Semantic_Type
  • Gene or Genome
Preferred_Name
  • CCL18 wt Allele
UMLS_CUI
  • C1706483
GO_Annotation
  • response to biotic stimulusGO:0009607TAS29-SEP-2003CGAP
  • antimicrobial humoral response (sensu Invertebrata)GO:0006960TAS29-SEP-2003CGAP
  • cell communicationGO:0007154TAS29-SEP-2003CGAP
  • chemokine activityGO:0008009TAS29-SEP-2003CGAP
  • cell-cell signalingGO:0007267TAS29-SEP-2003CGAP
  • signal transductionGO:0007165TAS29-SEP-2003CGAP
  • immune responseGO:0006955TAS29-SEP-2003CGAP
  • chemotaxisGO:0006935TAS29-SEP-2003CGAP
EntrezGene_ID
  • 6362
Legacy_Concept_Name
  • CCL18_wt_Allele
HGNC_ID
  • HGNC:10616
FULL_SYN
  • CCL18 wt AllelePTNCI
  • PARCSYNCI
  • CKb7SYNCI
  • AMAC1SYNCI
  • DCCK1SYNCI
  • MIP-4SYNCI
  • AMAC-1SYNCI
  • DC-CK1SYNCI
  • SCYA18SYNCI
  • Chemokine (C-C Motif) Ligand 18 wt AlleleSYNCI
Gene_Encodes_Product
  • Small Inducible Cytokine A18
DEFINITION
  • Human CCL18 wild-type allele is located in the vicinity of 17q11.2 and is approximately 7 kb in length. This allele, which encodes small inducible cytokine A18 protein, is involved in the chemotactic regulation of naive T cells, CD4+ and CD8+ T cells, and nonactivated lymphocytes involved in inflammatory processes. CCL18 allele may also be involved in B cell migration into lymph node follicles as well as humoral and cell-mediated immunity.NCI
DesignNote
  • CCL18 is induced by glucocorticoids, PMA, IL-4, IL-13, and IL-10 and expressed in lung, lymph nodes, placenta, bone marrow, dendritic cells, and macrophages.
code
  • C49723
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