About: Recombinant Interferon Beta

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Attributes	Values
rdf:type	Class
rdfs:label	Recombinant Interferon Beta
rdfs:subClassOf	Recombinant Interferon nodeID://b719327 nodeID://b719328 nodeID://b719329 nodeID://b719330 nodeID://b719331
Is_Related_To_Endogenous_Product	Interferon Beta
Semantic_Type	Amino Acid, Peptide, or Protein Pharmacologic Substance
Preferred_Name	Recombinant Interferon Beta
NSC_Code	373361 658933
UMLS_CUI	C0015980
CAS_Registry	77238-31-4
Accepted_Therapeutic_Use_For	multiple sclerosis
PDQ_Open_Trial_Search_ID	40468
PDQ_Closed_Trial_Search_ID	40468
Legacy_Concept_Name	Therapeutic_Interferon_Beta
FULL_SYN	Beta InterferonSYNCI Interferon, BetaSYNCI Interferon-BSYNCI Interferon BetaSYNCI Recombinant Interferon BetaPTNCI FeronFBNCI NaferonFBNCI Interferon-betaPTDCP31315 Human Interferon BetaSYNCI BetantroneFBNCI
DEFINITION	A recombinant protein which is chemically identical to or similar to endogenous interferon beta with antiviral and anti-tumor activities. Endogenous interferons beta are cytokines produced by nucleated cells (predominantly natural killer cells) upon exposure to live or inactivated virus, double-stranded RNA or bacterial products. These agents bind to specific cell-surface receptors, resulting in the transcription and translation of genes with an interferon-specific response element. The proteins so produced mediate many complex effects, including antiviral (the most important being inhibition of viral protein synthesis), antiproliferative and immune modulating effects. The recombinant therapeutic forms of interferon beta are interferon beta 1-a and interferon beta 1-b. (NCI05)NCI
code	C495
is rdfs:subClassOf of	INTERFERON BETA-1A,RECOMBINANT INTERFERON BETA-1B,RECOMBINANT
is someValuesFrom of	nodeID://b673915 nodeID://b683225 nodeID://b683226 nodeID://b683228 nodeID://b683230

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