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AttributesValues
rdf:type
rdfs:label
  • Loop Diuretic
rdfs:subClassOf
Semantic_Type
  • Chemical Viewed Functionally
Preferred_Name
  • Loop Diuretic
UMLS_CUI
  • C0354100
Legacy_Concept_Name
  • Loop_Diuretic
FULL_SYN
  • Loop DiureticPTNCI
DEFINITION
  • Any agent belonging to the class of loop diuretics. Loop diuretics block and inhibit the function of the sodium-potassium-chloride (Na+, K+, Cl-) cotransporter system in the thick ascending limb of the loop of Henle, thereby inhibiting the reabsorption of sodium, potassium, and chloride ions. This leads to an increase in the excretion of sodium, potassium, chloride, calcium, magnesium, ammonium and water.NCI
code
  • C49184
is rdfs:subClassOf of
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