About: Bowman-Birk Inhibitor Concentrate

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Attributes	Values
rdf:type	Class
rdfs:label	Bowman-Birk Inhibitor Concentrate
rdfs:subClassOf	Protease Inhibitor
Semantic_Type	Pharmacologic Substance
Preferred_Name	Bowman-Birk Inhibitor Concentrate
UMLS_CUI	C1706991
CAS_Registry	37330-34-0
ALT_DEFINITION	A substance being studied in the prevention of cancer. BBIC is made from soybeans, and is a type of serine proteinase inhibitor.NCI-GLOSS
PDQ_Open_Trial_Search_ID	433272
PDQ_Closed_Trial_Search_ID	433272
Legacy_Concept_Name	Bowman-Birk_Inhibitor_Concentrate
FULL_SYN	Bowman-Birk Inhibitor ConcentratePTNCI BBICPTNCI-GLOSSCDR0000512776 BBICABNCI Bowman-Birk inhibitor concentratePTNCI-GLOSSCDR0000468789 Proteinase Inhibitor, Bowman-Birk SoybeanPTDCP00610
DEFINITION	An extract of soybeans enriched in Bowman-Birk inhibitor (BBI), a soybean-derived, 71-amino acid, polypeptide and serine protease inhibitor with potential chemopreventive activity. Bowman-Birk inhibitor contains distinct inhibitory sites for trypsin and chymotrypsin. Although the exact mechanism by which BBI suppresses carcinogenesis is unknown, its antiproliferative activity appears to be linked to the chymotrypsin inhibitory region.NCI
code	C48381

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