About: Oral Cavity Squamous Cell Carcinoma

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About: Oral Cavity Squamous Cell Carcinoma Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Oral Cavity Squamous Cell Carcinoma
equivalentClass	nodeID://b636379
Semantic_Type	Neoplastic Process
Preferred_Name	Oral Cavity Squamous Cell Carcinoma
UMLS_CUI	C0585362
Neoplastic_Status	Malignant
Legacy_Concept_Name	Oral_Cavity_Squamous_Cell_Carcinoma
FULL_SYN	SCC of the Oral CavitySYNCI SCC of MouthSYNCI Oral Cavity Squamous Cell CarcinomaPTNCI Squamous Cell Carcinoma of the MouthSYNCI Oral Cavity SCCSYNCI SCC of the MouthSYNCI Squamous Cell Carcinoma of Oral CavitySYNCI SCC of Oral CavitySYNCI Mouth Squamous Cell CarcinomaSYNCI Mouth SCCSYNCI Squamous Cell Carcinoma of the Oral CavitySYNCI Squamous Cell Carcinoma of MouthSYNCI
DEFINITION	A squamous cell carcinoma arising from the oral cavity. It affects predominantly adults in their fifth and sixth decades of life and is associated with alcohol and tobacco use. Human papillomavirus is present in approximately half of the cases. It is characterized by a tendency to metastasize early to the lymph nodes. When the tumor is small, patients are often asymptomatic. Physical examination may reveal erythematous or white lesions or plaques. The majority of patients present with signs and symptoms of locally advanced disease including mucosal ulceration, pain, difficulty with speaking, chewing, and swallowing, bleeding, weight loss, and neck swelling. Patients may also present with swollen neck lymph nodes without any symptoms from the oropharyngeal tumor. The most significant prognostic factors are the size of the tumor and the lymph nodes status.NCI
code	C4833
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