About: Triamcinolone Acetonide     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Triamcinolone Acetonide
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Triamcinolone Acetonide
NSC_Code
  • 21916
UMLS_CUI
  • C0040866
CAS_Registry
  • 76-25-5
Accepted_Therapeutic_Use_For
  • Allergic Rhinitis
FDA_UNII_Code
  • F446C597KA
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 649799
PDQ_Closed_Trial_Search_ID
  • 649799
Chemical_Formula
  • C24H31FO6
Legacy_Concept_Name
  • Triamcinolone_Acetonide
FULL_SYN
  • Aristocort ABRNCI
  • Triamcinolone AcetonidePTNCI
  • TRIAMCINOLONE ACETONIDEPTFDAF446C597KA
  • 9-alpha-Fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dioneSNNCI
  • KenalogBRNCI
  • NasacortBRNCI
  • AllerNazeBRNCI
  • Triamcinolone AcetonidePTDCP00733
DEFINITION
  • The acetonide salt form of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activity. Triamcinolone acetonide binds to specific cytosolic glucocorticoid receptors and subsequently interacts with glucocorticoid receptor response element on DNA and alters gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished.NCI
code
  • C48027
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